Metabolic Syndrome
About the Disease
Abdominal Obesity-Metabolic Syndrome 1, also known as metabolic syndrome x, is related to mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome and nutritional deficiency disease, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Abdominal Obesity-Metabolic Syndrome 1 is MIR122 (MicroRNA 122), and among its related pathways/superpathways are Metabolism and IL-9 Signaling Pathways. The drugs Cilostazol and Captopril have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and adipocyte, and related phenotypes are hypertension and abdominal obesity
Common Targets
G8658 | G340146 | G6622 | G3949 | G6720 | G1012 | G5919 | G6524 | G283455 | G11001 | G4040 | G948 | G3620 | G7352 | G5478 | G1071 | G4023 | Diacylglycerol Acyltransferase (DGAT) (nonspecified subtype) | G23178 | G627 | G3636 | P6058 | G2339 | G4157 | G338557 | G151306 | G8379 | G5333 | G79689 | G1026 | G7040 | G2859 | G5550 | G3077 | G4285 | G7450 | P5859 | G2350 | G1021 | G139760 | G440 | G9055 | G3482 | G53373 | G3638 | G5163 | G80168 | G51738 | G2693 | G8882 | G11188 | G6721 | G10533 | G90379 | G22904 | G7099 | G22937 | G337 | G25770 | G2701 | G4330 | G59272 | G1581 | G7376 | G89872 | G7068 | G8694 | G1636 | G2864 | G670 | G116519 | G105375508 | G5733 | G574441 | Glycogen phosphorylase (nonspecified subtype) | G1601 | G1589 | G151 | G52 | G1269 | G4049 | G4247 | G2053 | G100126793 | G9370 | G4780 | G29881 | G1586 | G80339 | G5465 | G3479 | G183 | G4314 | G818 | Alpha-2 Adrenergic receptors (nonspecified subtype) | G7058 | G8660 | G1813 | G2100 | G2811 | G119032 | G10062 | G5164 | G2695 | G3106 | G6319 | G4217 | G54165 | G5443 | P9223 | G7299 | G2645 | G1312 | G187 | G10588 | G7357 | G3386 | G54901 | Casein kinase I (nonspecified subtype) | G79054 | G1374 | G23476 | G8395 | ADP-Ribosyl Cyclase/cyclic ADP-Ribose Hydrolase (ADPRC) (nonspecified subtype) | G2995 | G10628 | G116085 | G5178 | G887 | G10846 | Cholesterol esterase (nonspecified subtype) | G9619 | G3156 | G415116 | G3383 | Protein Tyrosine Phosphatase (PTP) (nonspecified subtype) | G3795 | G4296 | G10266 | G136 | G50507 | G134 | G222236 | G101928004 | G929 | G23411 | G6462 | G5152 | G4552 | AMP Deaminase (nonspecified subtype) | G2590 | G100874095 | Liver Bile Transporters (LBAT) (nonspecified subtype) | G3952 | G5481 | G79646 | G57619 | G1268 | G56853 | G19 | G7486 | G285 | G55691 | G51393 | G5468 | G55829 | G1490 | G1859 | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | G4887 | G255738 | P6320 | G4916 | G5740 | G3290 | P16126 | G118 | G80834 | G84439 | G5595 | G3375 | G345 | G6464 | G2876 | G952 | G3689 | G53345 | G7442 | G84722 | G5467 | G54986 | G4544 | G5166 | G27288 | G150 | G1803 | G2099 | G7046 | G2837 | P34664 | G3605 | G6403 | P11113 | G3643 | G9429 | G4734 | G5836 | G3480 | G490 | G2952 | G2696 | G116985 | G4914 | G5770 | G4878 | G51135 | G80351 | G231 | G9261 | G125 | G43 | G5054 | G100379251 | G2932 | G4159 | G10269 | G64240 | G7498 | G2646 | G2260 | G9021 | G22994 | G5340 | G10848 | G7391 | G2171 | G836 | G857 | G3630 | G728723 | G340024 | G100528021 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | G4985 | G57406 | G6133 | G7124 | G7021 | G51333 | G104326055 | Mitogen-Activated Protein Kinase (nonspecified subtype) | G4318 | G2908 | G4087 | G221895 | G51094 | G7466 | G514 | G9971 | G6554 | G3990 | G2101 | G79029 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | G4035 | G3062 | Pyruvate dehydrogenase kinase (nonspecified subtype) | G5894 | G2264 | G2878 | G2538 | G121278 | Trypsin (nonspecified subtype) | G4547 | G8644 | G412 | G23414 | G367 | G64241 | G53831 | G100507098 | G9759 | G3762 | G2982 | G140902 | G60312 | G10984 | G3953 | G345275 | G6256 | G144165 | G6833 | G7862 | G100131187 | G57104 | G3651 | G9040 | G2194 | G5292 | G467 | G2322 | G6927 | G3257 | G7421 | G5243 | G5799 | P11025 | Heat shock protein 70 (nonspecified subtype) | G3784 | G4846 | G4925 | G166929 | G4313 | G4524 | G4973 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | G4000 | G3303 | G3362 | G1195 | G6789 | G10642 | G1345 | G2028 | G6569 | G7029 | G2660 | G3586 | G5444 | G55915 | G9149 | G5167 | G105376523 | G32 | G335 | G3791 | G9475 | G23408 | G94241 | G6523 | P6348 | G5045 | G9365 | G10988 | Fatty Acid Binding Protein (nonspecified subtype) | G2548 | Cyclooxygenase (COX) (nonspecified subtype) | G154 | G3356 | G55010 | G4843 | G4036 | G9340 | G151987 | G718 | G185 | G7428 | G4853 | G57761 | G6755 | G723961 | G56606 | G3991 | G7066 | G8989 | Histone deacetylase (nonspecified subtype) | G177 | G1080 | G4160 | G4881 | G7422 | G3948 | G186 | G468 | G3172 | G55532 | P13024 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | G47 | G338 | G6414 | G54221 | G1588 | G1728 | G22795 | G3075 | P24924 | G79068 | G338442 | G3570 | G117194 | G6347 | G2155 | G5406 | G100505826 | G2914 | G3358 | Retinoid RXR receptor (nonspecified subtype) | G147 | G10644 | G56729 | G7350 | G2167 | G799 | G3305 | G3416 | G348 | alpha-Amylase (nonspecified subtype) | G240 | G105372629 | G1401 | G51185 | G85440 | G8195 | G10495 | G31 | G4837 | G619373 | G1585 | G1524 | G80774 | G2740 | G10891 | G1141 | G8878 | G3553 | G7048 | G283120 | G3107 | NADPH Oxidase (nonspecified subtype) | G1196 | G7015 | G9290 | G2169 | G3481 | G5697 | G3569 | G6928 | G29850 | G9388 | G9575 | G1113 | G3576 | Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) | G1032 | G3992 | G8315 | G6934 | G3162 | P10999 | G401237 | G4057 | G4312 | G8639 | G6714 | G1471 | G4353 | G80776 | G100616414 | G3119 | G7351 | G63892 | G4915 | G83756 | G11040 | G6518 | G6774 | G2642 | G3176 | G79072 | G57553 | Acetyl-CoA Carboxylases (ACC) (nonspecified subtype) | G1535 | G6696 | G6916 | G432 | G22933 | G3767
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Metabolic Syndrome, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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Osteopetrosis | Osteoporosis | Osteoporosis, Postmenopausal | Osteoporosis-pseudoglioma Syndrome | Osteosarcoma | Osteosclerosis | Otitis Externa | Otitis Media | Otopalatodigital Syndrome Type 2 | Otosclerosis | Ovarian Hyperstimulation Syndrome | Ovarian Sex Cord-stromal Tumor | Overactive Bladder | Pachyonychia Congenita | Paget's Disease Of The Breast | Pain | Palmoplantar Keratoderma | Palsy, Cerebral | Pancreatitis | Pancreatitis, Chronic | Pancytopenia | Panic Disorder | Panniculitis | Pantothenate Kinase-associated Neurodegeneration | Panuveitis | Papilledema | Papilloma | Papillon-Lefevre Syndrome | Papillorenal Syndrome | Papulopustular Rosacea | Paracoccidioidomycosis | Paraganglioma | Paraganglioma, Carotid Body | Paraplegia | Parapsoriasis | Parkinson Disease 6, Autosomal Recessive Early-onset | Parkinson's Disease | Parkinsonism | Paronychia | Paroxysmal Kinesigenic Dyskinesia | Paroxysmal Nocturnal Hemoglobinuria | Partington Syndrome | Parvovirus B19 Infection | PASLI 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